This week I am still sticking with the theme of Endometriosis. If you aren’t sure what this is, please check out my recent article on this topic. If you have Endometriosis and are wondering where to start, read last week’s article where I discussed 5 important food strategies to help with this condition.
This week is all about supplements. Remember, if you don’t have the basics in place (ie. diet & lifestyle) then supplements are going to do little to help. They offer support and can help stimulate certain pathways in the body but if you eat junk, don’t sleep or exercise and are overwhelmed by stress, then don’t waste your money on supplements.
Start with the basics and come back to this article when those things are in place.
In the previous article I discussed cruciferous vegetable and how they contain a compound that is extremely effective at detoxing estrogen out of the body. DIM is the compound I was referring to.
I have found DIM to be one of the most powerful supplements for reducing excess estrogen. It is extremely effective, so this should only be used if you have been tested and know your estrogen levels are too high.
Not only does DIM lower estrogen overall but it also shifts estrogen metabolism to healthy pathways that protect you from estrogen dominant cancers.
Some people will recommend using Indol-3-Carbinol (I3C) instead of DIM. I3C is the precursor for DIM and in theory can be metabolized to DIM to have a similar effect. In my experience I3C is not nearly as effective as DIM and I don’t recommend it unless you cannot tolerate DIM.
My favorite products are Designs for Health DIM-Avail and Pure Encapsulations DIM Detox
Curcumin comes from Turmeric. It is a powerful antioxidant and anti-inflammatory. Taking curcumin can help with some of the inflammation and painful side effects of endometriosis.
Curcumin has been found effective at reducing prostaglandins which promote inflammation.
In this study, researchers found that curcumin inhibited the growth of endometrial cells by lowering the production of Estradiol (the body’s most potent estrogen). This study was done in vitro so the results may be limited.
Curcumin is also powerful at detoxifying the liver. This is important as the liver is responsible for clearing excess hormones from the blood. Too much estrogen can be a result of poor liver clearance, resulting in excess estrogen floating around the blood.
N-Acetyl-Cysteine is a precursor for glutathione. Glutathione is your body’s most powerful anti-oxidant and detoxifier. It is needed to keep the liver free of toxins and reduce damage from free radical production.
Taken directly, glutathione is poorly absorbed but we can work with glutathione precursors to boost glutathione levels. NAC is a fantastic for boosting liver health and detoxification. Since estrogen dominance is tied to poor liver function, NAC is a good place to start.
This is a very powerful supplement for any women with Endometriosis or estrogen dominance. As discussed in my previous article, harmful gut bacteria can produce a lot of the enzyme Beta-Glucuronidase which can break the bond between excreted estrogen and glucuronic acid (the way in which estrogen in moved out of the body), thereby re-activating the excreted hormone and sending it back into circulation.
Calcium D-Glucarate helps keep estrogen bound to glucuronic acid so that it can be easily excreted from the body.
Digestive Enzymes with Ox Bile
After the liver detoxifies hormones, it dumps them into the bile so they can be excreted from the body. If a woman has bile insufficiency then detoxification is impaired and estrogen is left to recirculate around the body.
A sign that you may have a bile deficiency is the inability to digest fat. If eating a fat meal makes you feel bloated or nauseous than you can benefit from taking a digestive enzyme with ox bile.
If you have had your gallbladder removed, you are likely struggling with bile production as well. My favorite product is Thorne Research Bio-Gest.
If you would like to be hooked up with an account to order any of the supplements I discussed in this article, please sent me an email at firstname.lastname@example.org